When a group of college students take part in a clinical drug trial, an unexpected side effect of the experimental medicine gives them terrifying visions of their own deaths…which begin to come true. As they scramble to escape their fate, they discover that the killer is among them and shares their ability to see the future – only he seems to be one step ahead of their efforts to survive.
The unemployed waitress Anna joins a group of college student in the isolated facility of the Hallorann Laboratory to participate in the research of Dr. Jerrems and raise some money. Dr. Jerrems explains that only half of them will be injected with the drug – the other half will be injected with harmless placebo. Anna befriends Den, Kristen and Marcus and soon Marcus and Kristen are affected by an unexpected side effect and have the ability to see the future. Anna is also affected and discovers that she can see the other youngsters dying and Dr. Jerrems locks her in a room. Meanwhile a stranger breaks in the facility and there is bloodshed in the place. Den, Marcus, Kristen and Scratch try to flee but Den wants to save Anna. Who might be the killer and what is his motive?